First, free glutamate fed to neonates, infants, and young children can cross the extremely porous blood brain barrier (BBB) of the arcuate nucleus of the hypothalamus, enter the brains of the unborn and the very young, and wipe out brain cells that were designed to regulated weight control. In this scenario, obesity happens when the endocrine system in charge of weight control is damaged. In this scenario, the endocrine system in charge of weight control is damaged when excitotoxic glutamic acid gains access to the undeveloped brains of the unborn and the newborn. And damage to the endocrine systems of the unborn and the newborn is brought about by feeding excitotoxic glutamic acid and excitotoxic aspartic acid (as in aspartame) to the unborn and the newborn through the diets of their pregnant and lactating mothers.
Think about it. You can’t see brain damage caused by free glutamate fed to the unborn (fetus) or the newborn by a pregnant or lactating mother. You can’t see the brain damage that disrupts the endocrine system designed to protected both males and females from reproductive disorders (infertility). You can’t see the brain damage that disrupts the endocrine system designed to regulated insulin and glucose secretion, appetite, satiety and weight control. You can’t see the damage done to an endocrine system designed to prevent obesity.
Just as a broken switch on your table lamp might be repairable, a damaged endocrine system might also be fixable. But if the switch had literally been destroyed, much as glutamate receptors are wiped out by the excessive stimulation of glutamic acid, the switch itself would not be fixable; and neither would those areas of the arcuate nucleus that have been wiped out by glutamic acid. No amount of diet or exercise will make up for an endocrine system gone missing.
The literature is full of studies of the role that glutamic acid plays in disease and disability. Yet, in considering interventions for disease and disability caused or exacerbated by free glutamic acid, the brain damage data from the 60s and 70s have been systematically ignored.
And when at the age of 20 or so you try to have children, you probably won’t even think that it might have been the free glutamate that your mother passed on to you when you were in the womb, or the free glutamate in your mother’s milk or in the infant formula fed to you that caused your infertility. And when, as you grow into maturity, you begin to gain weight, uncontrollably, you probably won’t think that it might have been the free glutamate that your mother passed on to you when you were in the womb, or the free glutamate in your mother’s milk or in the infant formula fed to you, that caused your obesity.
Data gathered by independent researchers in the 1960s and the 1970s verify that what is said here is true. Yet we hear absolutely nothing about this -- largely because those who profit from the manufacture and sale of free glutamate want it that way, and have the power to get what they want.
Data demonstrating glutamate-induced obesity have been suppressed by the glutamate industry and their friends at the FDA.
More obvious than glutamate-induced brain damage and endocrine disruption, is a second way in which free glutamate can trigger obesity. Migraine headache, asthma, skin rash, seizures, and irritability, might be noticed after eating something that contained free glutamate -- something containing monosodium glutamate, hydrolyzed pea protein, autolyzed yeast, maltodextrin, or natural flavors, for example. And if a person would really pay attention, he or she might observe that on days when a lot of processed food was eaten, there would be weight gain. Ingestion of free glutamate is known to affect both insulin and glucose secretion. Both are relevant to obesity. And then there’s the addictive quality of all that free glutamate in processed foods. It's free glutamate that enhances the flavor of food. It tastes so good you really can’t stop eating food with free glutamate in it.
Is free glutamate the only cause of obesity? Certainly not. A blow to the head might damage nerves in the arcuate nucleus of the hypothalamus. GMOs and glyphosate might do the same thing. Fat and sugar, carbohydrates in excess, and lack of exercise certainly play a role. But free glutamate passed to the unborn and the newborn is, without question, a cause of obesity – the root cause of the obesity epidemic.