Subject: FW: Question
Date: 10/17/2008 5:19:31 A.M. Pacific Daylight Time (Me
Reply To: Adrienne Samuels

Dear Dr. Samuels,

This is a response to your e-mail inquiry of October 9, 2008, in which you asked if there is a standard of identity listed in the Code of Federal Regulations (CFR) for monosodium glutamate (MSG).
The CFR does not specify a standard of identity for MSG used in food.  However, FDA expects that the MSG manufactured for use in food would conform to the specifications defined in the Food Chemicals Codex (FCC).  The FCC defines the qualities of food-grade chemicals in terms of identity, strength, and purity based on the elements of safety and GMP.  For your convenience, I have attached the most recent monograph for food-grade MSG published in the 6th edition of the FCC.

There are numerous publicly available references that address the chemistry, safety, and food use of MSG that you may find to be helpful in further understanding the use of MSG.

I hope you find this information helpful.


Molly Harry, M.S.
[Food and Drug Administration]
Division of Biotechnology andGRAS Notice Review


The copy of the Food Chemicals Codex sent by Ms. Harry has resisted reproduction.